I have a brother in law who has been diagnosed with cataplexy and narcoplexy, where he starts quivering and slowly loses control of his body and goes into a sleep, which causes him to drop to the ground with mild seizures while he is out. He lives alone (59 years old), but has smoked cannabis since he (we) were teenagers. He still smokes, and is on medication twice a day for this condition, but if he misses those meds by even half an hour, he is at risk of these seizures. The sad part is, these seizures are usually brought on by the smallest emotional change, usually tension, excitement or, the worst thing, if something he finds funny and is the least bit tickled about and starts to laugh, this process will immediately begin. Does anyone know if this kind of condition is treatable with cbd oil’s or concentrates? As I said, he smokes weed, and often grows his own, but he does it for the high and relaxation advantage, since he is basically home-bound due to this condition ending his work career about 4 years ago. Thanks for any replies. I’d be overjoyed if I could tell him there’s a possible solution to the problem other than his prescriptions. Or even if it worked WITH his meds to keep from having to live such a sedentary life.
Congrats, you got to the most confusing part of CBD — figuring out the dosage. Unfortunately, you’ll have to do a little bit of math. First, you need to find out how many mg’s of CBD does your product have per milliliter. For example, when you buy CBD oil from a licensed producer in Canada, the product label says “CBD content 20 mg/ml”. Now, 1 ml is usually made up of 20 drops, so (using our CBD oil as an example) for every 20 drops you have 20 mg of CBD. This means that one drop contains one milligram of CBD, so it’s easy to figure out how many drops you need.
If you have ever suffered from anxiety, then you know that it is awful, and it would be the same for your dog too. Many dogs suffer from anxiety and have been known to be depressed and extremely anxious in certain situations, such as when their owner leaves. This can result in destructive behaviors such as chewing objects, urinating, pacing, and more. CBD helps because it is a relaxing stimulant that calms your pet.
We don't get many returns, so we don't require any forms or documents; just be sure to include something with your name or order number so that we know which order to refund. We offer a 30-day return period for all our products if they are returned to us unopened and unused. Also, for many of our products, such as PurCBD and PurOtic, we offer a 30-day money back guarantee even if they are opened and completely used.

Cannabis (/ˈkænəbɪs/) is a genus of flowering plants in the family Cannabaceae. The number of species within the genus is disputed. Three species may be recognized: Cannabis sativa, Cannabis indica, and Cannabis ruderalis; C. ruderalis may be included within C. sativa; all three may be treated as subspecies of a single species, C. sativa;[1][2][3][4] or C. sativa may be accepted as a single undivided species.[5] The genus is widely accepted as being indigenous to and originating from Central Asia, with some researchers also including upper South Asia in its origin.[6][7]

Recent European Commission proposals to change its subsidy regime for hemp contained the following negative evaluation of hemp seed: “The use of hemp seed ... would, however, even in the absence of THC, contribute towards making the narcotic use of cannabis acceptable... In this light, subsidy will be denied producers who are growing grain for use in human nutrition and cosmetics.”
“We’re so pleased farmers across America now have the freedom to consider integrating this important crop into their production, particularly with the trade concerns around other crops such as soybeans, corn, and wheat," said Elizabeth Hogan, VP of Brands at GCH Inc., the company behind Willie Nelson’s cannabis brands. Hemp legalization will transform it from niche interest and return it to cash crop status.
Researchers have shown that CBD carries many potential health benefits. These health benefits include; Reducing inflammation & pain, improving circulation, promoting bone growth, reducing stress levels and anxiety, reducing nausea and stimulating the appetite, increasing cognitive functions, lowering blood sugar levels, reducing seizures, inhibiting cancer cell growth, and improving overall wellness and health for your pet.
Hemp stalk is baled for transportation and long-term storage using traditional farming balers. Large round balers are best for hemp because they allow for more thorough drying as they don’t pack the hemp as tightly as square balers. Hemp should be stored in a dry environment in conditions intended to reduce as much absorbable air moisture as possible. It’s also important to check for wet patches during baling to further avoid mold.
Running a profitable and legal cannabis dispensary is entirely possible but not at all easy. The regulatory labrynth is tough to navigate, startup costs are usually significant, the taxes are brutal and the competition is fierce. Building a successful cannabis business means understanding, before you even get started, the many ways this industry is unique.

The ECS is responsible for setting the baseline activity levels of our immune system and nervous system, which then work to maintain our health. When the ECS falls out of whack, the systems that are regulated by it can begin to malfunction. CBD promotes the normal health and function of the endocannabinoid system, so it’s possible that CBD can help to alleviate the symptoms of conditions that are caused by dysfunction of the endocannabinoid system.
For epilepsy: A prescription cannabidiol product (Epidiolex) has been used. The recommended starting dose is usually 2.5 mg/kg twice daily (5 mg/kg/day). After one week the dose can be increased to 5 mg/kg twice daily (10 mg/kg/day). If the person doesn't respond to this dose, the maximum recommended is 10 mg/kg twice daily (20 mg/kg/day). In some research, higher doses of up to 50 mg/kg daily have been used. There is no strong scientific evidence that nonprescription cannabidiol products are beneficial for epilepsy.
Following an 1836–1840 travel in North Africa and the Middle East, French physician Jacques-Joseph Moreau wrote on the psychological effects of cannabis use; he was a member of Paris' Club des Hashischins.[citation needed] In 1842, Irish physician William Brooke O'Shaughnessy, who had studied the drug while working as a medical officer in Bengal with the East India company, brought a quantity of cannabis with him on his return to Britain, provoking renewed interest in the West.[205] Examples of classic literature of the period featuring cannabis include Les paradis artificiels (1860) by Charles Baudelaire and The Hasheesh Eater (1857) by Fitz Hugh Ludlow.

In 2015, almost half of the people in the United States had tried marijuana, 12% had used it in the past year, and 7.3% had used it in the past month.[31] In 2014, daily marijuana use amongst US college students had reached its highest level since records began in 1980, rising from 3.5% in 2007 to 5.9% in 2014 and had surpassed daily cigarette use.[251]

Understanding CBD’s analgesic, or pain-relieving, interactions with the ECS can shed light on CBD’s other interactions and effects. Importantly, the ECS participates in our bodies’ pain processing, but when CBD is introduced to our ECS, it stops the body from absorbing a pain-regulating compound known as anandamide — one of our body’s’ own natural cannabinoid molecules. Inhibiting the absorption of this compound shunts excess quantities into the bloodstream that in turn reduces pain. One study has revealed that CBD targets alpha-3 (α3) glycine receptors to suppress chronic pain and inflammation associated with dysfunctional glycine receptors, which are an important target for pain processing in the spine. In both humans and animal models, CBD has been shown to have a variety of anti-inflammatory properties.
Based on world production of fibers in 1999, about 54.5% was synthetic (of which 60.3% was polyester), 42.9% was plant fiber (of which 78.5% was cotton), and 2.6% was wool (Karus 2000). In addition to cotton, flax is the only other significant plant fiber crop grown in temperate regions of the world (kenaf has received some enthusiastic backing in the southern US in recent years, but is most cheaply produced in India, Bangladesh, and China). Flax held 2.7% of the world plant fiber market in 1999, while hemp had only 0.3% (Karus 2000). Hemp fiber can potentially replace other biological fibers in many applications, but also, as noted below, can sometimes compete with minerals such as glass fiber and steel. As forests diminish, cultivation of annual plants as fiber sources is likely to increase. While crop residues like cereal straw will probably supply much of the need, specialty fiber plants such as hemp also have potential. The four conditions that will need to be met are (after Bolton 1995): (1) the material should be produced at a large enough scale; (2) the price should be low enough; (3) the fiber characteristics should be adequate for the end use; and (4) proven technology should be available for the processing of the new raw material. Of these criteria only point 3 is adequately met at this time for hemp in North America, but this is to be expected in a crop that has only begun to be cultivated after an absence of many years.
Modern decorticating techniques employ steam explosion (treating the fibers with steam through a pressurized chamber) and ultrasonic breaking (breaking down fibers using ultrasonic waves) to maintain the integrity of the fibers throughout the process. These techniques are not as harsh on the stalks and allow processors to use the fibers on cotton and wool processing machinery.
Success stories like Oliver’s are everywhere, but there’s not a lot of data to back up those results. That’s because CBD comes from cannabis and, like nearly all other parts of the plant, is categorized by the Drug Enforcement Agency (DEA) as a Schedule 1 drug—the most restrictive classification. (Others on that list: heroin, Ecstasy, and peyote.) This classification, which cannabis advocates have tried for years to change, keeps cannabis-derived products, including CBD, from being properly studied in the U.S.

^ Advocates of legalizing marijuana for recreational use, such as Illinois state Senator Heather Steans, has said that legalizing it would help reduce such hazardous added drugs: "Over 95 percent are buying it on the black market. You don’t know what you’re buying. It’s not a safe product. We’ve seen it laced with rat poison, fentanyl, all sorts of things. It’s funding the cartels and other criminal activity."[82]
Cannabis, (genus Cannabis), plant belonging to the family Cannabaceae of the nettle order (Urticales). By some classifications, the genus Cannabis comprises a single species, hemp (Cannabis sativa), a stout, aromatic, erect annual herb that originated in Central Asia and is now cultivated worldwide, including in Europe, southern Asia, the Middle East, India, Africa, and the Americas. A tall canelike variety is raised for the production of hemp fibre, while the female plant of a short branchier variety is prized as the more abundant source of the psychoactive substance tetrahydrocannabinol (THC), the active ingredient of marijuana.
To name just a few: Animal research and small-scale human studies have pointed to CBD's anti-anxiety and anti-inflammatory properties, NPR reports. A study is underway to see how CBD helps patients with PTSD and alcohol use disorder, and another is exploring how CBD might help curb drug cravings in people with opioid addiction. Cannabinoids like CBD may also be effective at treating cancer-related side effects, according to the National Institutes of Health.
The overall effect is not assured because, like cannabis — which is illegal under U.S. federal law although some states have allowed medical or recreational use — states will continue to be able to enact laws related to industrial hemp, allowing for a potential patchwork of legislation across the country. Other questions remain in terms of how exactly the Agriculture Department will regulate the plant.

In Canada, the methodology used for analyses and sample collection for THC analysis of hemp plantings is standardized (at the Health Canada/Therapeutics Program/Hemp web site at www.hc-sc.gc.ca/hpb-dgps/therapeut/htmleng/hemp.html, see “Industrial Hemp Technical Manual” for procedures on sampling plant materials and chemical procedures for determining THC levels). The regulations require that one of the dozen independent laboratories licensed for the purpose conduct the analyses and report the results to Health Canada. Sample collection is also normally carried out by an independent authorized firm. The Canadian system of monitoring THC content has rigidly limited hemp cultivation to cultivars that consistently develop THC levels below 0.3%.
μ-Opioid receptor agonists (opioids) (e.g., morphine, heroin, hydrocodone, oxycodone, opium, kratom) α2δ subunit-containing voltage-dependent calcium channels blockers (gabapentinoids) (e.g., gabapentin, pregabalin, phenibut) AMPA receptor antagonists (e.g., perampanel) CB1 receptor agonists (cannabinoids) (e.g., THC, cannabis) Dopamine receptor agonists (e.g., levodopa) Dopamine releasing agents (e.g., amphetamine, methamphetamine, MDMA, mephedrone) Dopamine reuptake inhibitors (e.g., cocaine, methylphenidate) GABAA receptor positive allosteric modulators (e.g., barbiturates, benzodiazepines, carbamates, ethanol (alcohol) (alcoholic drink), inhalants, nonbenzodiazepines, quinazolinones) GHB (sodium oxybate) and analogues Glucocorticoids (corticosteroids) (e.g., dexamethasone, prednisone) nACh receptor agonists (e.g., nicotine, tobacco, arecoline, areca nut) Nitric oxide prodrugs (e.g., alkyl nitrites (poppers)) NMDA receptor antagonists (e.g., DXM, ketamine, methoxetamine, nitrous oxide, phencyclidine, inhalants) Orexin receptor antagonists (e.g., suvorexant)
Hemp seeds can be eaten raw, ground into hemp meal, sprouted or made into dried sprout powder. Hemp seeds can also be made into a liquid and used for baking or for beverages such as hemp milk and tisanes.[15] Hemp oil is cold-pressed from the seed and is high in unsaturated fatty acids.[16] The leaves of the hemp plant, while not as nutritional as the seeds, are edible and can be consumed raw as leafy vegetables in salads, and pressed to make juice.[17]
Marijuana has in fact been grown for medicinal research in North America by both the Canadian (Fig. 40) and American governments, and this will likely continue. The possibility of marijuana becoming a legal commercial crop in North America is, to say the least, unlikely in the foreseeable future. Nevertheless the private sector is currently producing medicinal marijuana in Europe and Canada, so the following orientation to marijuana as a potential authorized crop is not merely academic.
CatryNA49; Cannabis, like Opium poppies, and the substances derived from these plants, were also made illegal as a means of preventing white females, from being seduced, and or raped by male members of minority races; seriously ! In the early 70s Nixon administration officials oversaw the expansion of drug laws, as a means of legally repressing the two groups of Americans, that administration deemed to be their biggest foes; those groups being, African Americans, and the antiwar left. We know the drug war, just like the earlier less repressive drug laws, was initiated as a means of legal political, and racial repression because of the fact that a Nixon adm. official is on film, admitting as much. You can Google that film if you like. Now despite the truth about the drug war being admitted on film, for anyone in the world who has internet access can see, the drug war continues to be waged by politicians; the same politicians by the way, that tens of millions of Americans continue to vote for. I should add, that in the last presidential election, the candidate who promised to refuel the drug war, was the candidate who won that election. Of course what else could you expect, being that we live in the land of the free and the home of the brave ?!
The scientific debate regarding taxonomy has had little effect on the terminology in widespread use among cultivators and users of drug-type Cannabis. Cannabis aficionados recognize three distinct types based on such factors as morphology, native range, aroma, and subjective psychoactive characteristics. Sativa is the most widespread variety, which is usually tall, laxly branched, and found in warm lowland regions. Indica designates shorter, bushier plants adapted to cooler climates and highland environments. Ruderalis is the informal name for the short plants that grow wild in Europe and Central Asia.
If It Sounds Too Good to Be True… Ah, the online CBD dog products. Sounds too good to be true, right? The CBD you get online comes from industrial (or “agricultural”) hemp that might have originated in your home state, or it might have come from overseas or another processing facility where the CBD was extracted through less-than ideal processes. There are several ways to extract CBD from hemp, but one of the quickest and cheapest involves using solvents such as butane and hexane, which can leave a toxic residue if not properly handled. That’s not to say all online products should be distrusted, but definitely do your research on the company, how they make their product, their claims, and what unbiased reviewers are saying.

As a musician I’ve spent literally countless hours in the studio practicing, often contorting limbs in unnatural positions for up to 10 hours a day sometimes daily for periodic stretches. After 15 years of this I have enormous neuromuscular damage to my neck, shoulders, back, and pectoral muscles. My neck especially causes me enormous pain every day of my life and this cbd oil literally makes my life possible. Because of this cream I am Able to live without pain. The only way for me to maintain strength enough in the effected areas in order to still play in the studio and live shows I must keep up an extremely rigorous physical therapy routine every day to keep everything stretched out and limber enough to work. Before I found this cbd cream I was in so much pain it was very difficult to make myself get started on my exercise every day because of how much it hurts, not even to mention the absolutely horrific migraines I had all the time. Cbd is an absolute lifesaver, I would be in a dark place without it.

Medical marijuana refers to the use of the Cannabis plant as a physician-recommended herbal therapy as well as synthetic[191] THC and cannabinoids. So far, the medical use of cannabis is legal only in a limited number of territories, including Canada,[38] Belgium, Australia, the Netherlands, Spain, and many U.S. states. This usage generally requires a prescription, and distribution is usually done within a framework defined by local laws. There is evidence supporting the use of cannabis or its derivatives in the treatment of chemotherapy-induced nausea and vomiting, neuropathic pain, and multiple sclerosis. Lower levels of evidence support its use for AIDS wasting syndrome, epilepsy, rheumatoid arthritis, and glaucoma.[78]
Medical cannabis (or medical marijuana) refers to the use of cannabis and its constituent cannabinoids, to treat disease or improve symptoms. Cannabis is used to reduce nausea and vomiting during chemotherapy, to improve appetite in people with HIV/AIDS, and to treat chronic pain and muscle spasms.[103][104] Cannabinoids are under preliminary research for their potential to affect stroke.[105]
CBD refers to cannabidiol which is a certain compound found in cannabis referred to as a cannabinoid. Cannabis contains nearly 400 different compounds and many of those are specific to the cannabis species, these are what are known as cannabinoids. Hemp oil is special though as it is the key piece to many of the medical benefits we know medical marijuana to produce.  
Will hemp commercial cultivation resume in the US in the foreseeable future? This is difficult to judge, but the following considerations suggest this might occur: (1) increasing awareness of the differences between industrial hemp and marijuana; (2) growing appreciation of the environmental benefits of hemp cultivation; (3) continuing demonstration of successful hemp cultivation and development in most of the remaining western world; all the G8 countries, except the US, produce and export industrial hemp; and (4) increasing pressure on state and federal governments to permit hemp cultivation by farmers, particularly wheat, corn, and tobacco farmers in desperate need of substitute crops, but also for rotation crops to break pest and disease cycles.
Preliminary work in Germany (noted in Karus and Leson 1994) suggested that hemp could be grown on soils contaminated with heavy metals, while the fiber remained virtually free of the metals. Kozlowski et al. (1995) observed that hemp grew very well on copper-contaminated soil in Poland (although seeds absorbed high levels of copper). Baraniecki (1997) found similar results. Mölleken et al. (1997) studied effects of high concentration of salts of copper, chromium, and zinc on hemp, and demonstrated that some hemp cultivars have potential application to growth in contaminated soils. It would seem unwise to grow hemp as an oilseed on contaminated soils, but such a habitat might be suitable for a fiber or biomass crop. The possibility of using hemp for bioremediation deserves additional study.
That's not to say CBD-infused creams definitely won't reduce your acute pain or muscle soreness. That's because pretty much all of these creams on the market right now have other scientifically-proven analgesic compounds, like menthol, camphor, and capsaicin which are also found in other, non-CBD topical pain relievers. "Any cream with a heating or cooling sensation desensitizes the nerves to pain by distracting them with stimuli on top," Dr. Colberg explains. Plus you're often massaging the area as you apply, which improves circulation and reduces muscle spasms, he adds.
Last year, the Hemp Industries Association (HIA) estimated the total retail value of all hemp products sold in the U.S. at $620 million. Sadly, all of the raw hemp materials were imported from other countries. (More on that later.) Hemp is an attractive rotation crop for farmers. As it grows, hemp breathes in CO2, detoxifies the soil, and prevents soil erosion. What’s left after harvest breaks down into the soil, providing valuable nutrients.
CBD strains can be consumed just as you would THC strains. You can smoke or vaporize CBD-rich flower, eat a CBD-infused edible, swallow a CBD oil capsule, apply a CBD lotion, or use a CBD tincture sublingually. Hemp products also contain CBD, though it is a less efficient source and lacks the beneficial chemical diversity of cannabis-derived CBD products (more on that here).
Common treatments for fibromyalgia are anti-inflammatory medications, opioid pain medications, and corticosteroids. A 2011 study that focused on CBD treatment for fibromyalgia produced very promising results for future uses in treatment. Half of the 56 participants used Cannabidiol, while the other half used traditional methods to treat their condition. Those that used cannabis saw a great reduction in their symptoms and pain, while those using traditional methods didn’t see much of an improvement.